What does the human gene H2AFY code?

 Question: What does the human gene H2AFY code? How many amino acids are present in isoform 1 of this protein?

Solution:

The human gene H2AFY codes for the protein Core Histone Macro-H2A1. In a subset of nucleosomes, it replaces the conventional H2A histones. It represents the transcription and inactivates the stable X-chromosome. Multiple transcript variants coding for different isoforms are formed because of alternative splicing. And expression of these isoforms is associated with different type of cancers and tumors. For example hepatocellular cancer.

372 number of amino acids are present in isoform 1 of this protein.